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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASPM All Species: 17.88
Human Site: T2563 Identified Species: 56.19
UniProt: Q8IZT6 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZT6 NP_060606.3 3477 409800 T2563 A S I V I Q S T Y R M Y R Q Y
Chimpanzee Pan troglodytes P62293 3477 409724 T2563 A S I I I Q S T Y R M Y R Q Y
Rhesus Macaque Macaca mulatta P62292 3479 410087 T2566 A A I I I Q S T Y R M Y R Q Y
Dog Lupus familis XP_537130 3407 401187 T2494 A A I I I Q S T Y R M Y R Q Y
Cat Felis silvestris
Mouse Mus musculus Q8CJ27 3122 364103 G2292 K I Q S S Y R G W V V R K R V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506218 2691 320176 V1861 S L K T A A V V C Q R R Y R A
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001116845 3391 394231 S2521 A S V I I Q A S F R M Y Q Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787918 3597 412342 C2648 M A T K I Q A C F R G Y V Q H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 95.8 79.1 N.A. 63.2 N.A. N.A. 50.1 N.A. N.A. 39 N.A. N.A. N.A. N.A. 31.4
Protein Similarity: 100 99.4 97.9 87.8 N.A. 74.8 N.A. N.A. 63.5 N.A. N.A. 59.9 N.A. N.A. N.A. N.A. 53
P-Site Identity: 100 93.3 86.6 86.6 N.A. 0 N.A. N.A. 0 N.A. N.A. 53.3 N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: 100 100 100 100 N.A. 26.6 N.A. N.A. 20 N.A. N.A. 93.3 N.A. N.A. N.A. N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 63 38 0 0 13 13 25 0 0 0 0 0 0 0 13 % A
% Cys: 0 0 0 0 0 0 0 13 13 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 13 0 0 13 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % H
% Ile: 0 13 50 50 75 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 13 0 13 13 0 0 0 0 0 0 0 0 13 0 0 % K
% Leu: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 13 0 0 0 0 0 0 0 0 0 63 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 13 0 0 75 0 0 0 13 0 0 13 75 0 % Q
% Arg: 0 0 0 0 0 0 13 0 0 75 13 25 50 25 13 % R
% Ser: 13 38 0 13 13 0 50 13 0 0 0 0 0 0 0 % S
% Thr: 0 0 13 13 0 0 0 50 0 0 0 0 0 0 0 % T
% Val: 0 0 13 13 0 0 13 13 0 13 13 0 13 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 13 0 0 50 0 0 75 13 0 50 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _